Researchers at Rutgers Biomedical and Health Sciences have found a potential new way to treat sepsis using electro-acupuncture. Sepsis is a serious inflammatory reaction to an infection and is one of the leading causes of death in hospital settings. Looking far a way to reduce this inflammatory response the researchers set out to work with the vagus nerve since it is involved in managing inflammation.
“The researchers already knew that stimulation of one of the body’s major nerves, the vagus nerve, triggers processes in the body that reduce inflammation, so they set out to see whether a form of acupuncture that sends a small electric current through that and other nerves could reduce inflammation and organ injury in septic mice. Ulloa explains that increasing the current magnifies the effect of needle placement, and notes that electrification is already FDA-approved for treating pain in human patients.” – via Acupuncture holds promise for treating inflammatory disease, study shows — ScienceDaily.
In the animal study researchers used electroacupuncture (EA) to stimulate the sciatic nerve (as a way to create a vagal response) in mice with sepsis. What they found was a release of cytokines (these molecules limit inflammation) and dopamine production in the adrenal medulla. About half the mice receiving acupuncture survived for at least a week where there were no survivors in the the group that did not receive acupuncture.
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While this is an exciting development – acupuncture alone is unlikely to help most people with sepsis as it appears to be dependent on adrenal function, which in most patients with sepsis is drastically reduced. However, uncovering these physiological mechanisms that occur with acupuncture are important in the treatment of other inflammatory conditions.
“On the one hand, he says, this research shows physical evidence of acupuncture’s value beyond any that has been demonstrated before. His results show potential benefits, he adds, not just for sepsis, but treating other inflammatory diseases such as rheumatoid arthritis, osteoarthritis and Crohn’s disease.” -via Acupuncture holds promise for treating inflammatory disease, study shows — ScienceDaily.
abstract here: http://www.nature.com/nm/journal/v20/n3/full/nm.3479.html
